Ghr CLIA Kit for Rat(Rattus norvegicus) | EIAab.comGhr CLIA Kit for Rat(Rattus norvegicus)

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Ghr (Gene name),

Growth hormone receptor (Protein name ), GHR_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ghr;

Protein name:

Growth hormone receptor(GH receptor);

Alternative:

Somatotropin receptor;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

On growth hormone (GH) binding, forms homodimers and binds JAK2 via a box 1-containing domain. Binding to SOCS3 inhibits JAK2 activation, binding to CIS and SOCS2 inhibits STAT5 activation.

Function:

The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

Subcellular Location:

Isoform 2 Secreted Membrane Mainly secreted. In adipose tissue, isoform 2 is mostly membrane associated.

Protein Attributes:

Sequence length:

638

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

638:

KSPRGLILNA | TALPLPDKKK | FLSSCGYVST | DQLNKIMQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.2178

SMR:

P16310

String:

P16310

KEGG:

rno:25235

Pfam:

PF09067

Uniprot:

P16310

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ELISA Kit for Rat GH receptor

Cat.:

E1036h

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Packing:

96T

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ELISA Kit for Rat GH receptor

Cat.:

E1036p

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Packing:

96T

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ELISA Kit for Rat GH receptor

Cat.:

E1036m

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96T

ELISA Kit for Rat GH receptor

Cat.:

E1036c

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96T

ELISA Kit for Rat GH receptor

Cat.:

E1036d

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96T

ELISA Kit for Rat GH receptor

Cat.:

E1036r

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96T

ELISA Kit for Rat GH receptor

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ELISA Kit for Rat GH receptor

Cat.:

E1036b

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Packing:

96T

CLIA Kit for Rat GH receptor

Cat.:

U1036d

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96T

CLIA Kit for Rat GH receptor

Cat.:

U1036r

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96T

CLIA Kit for Rat GH receptor

Cat.:

U1036c

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96T

CLIA Kit for Rat GH receptor

Cat.:

U1036p

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96T

CLIA Kit for Rat GH receptor

Cat.:

U1036m

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96T

CLIA Kit for Rat GH receptor

Cat.:

U1036b

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96T

CLIA Kit for Rat GH receptor

Cat.:

U1036h

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96T

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CLIA Kit for Rat GH receptor

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Polyclonal Antibody for Rat GH receptor

Cat.:

P1036Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat GH receptor

Cat.:

P1036Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat GH receptor

Cat.:

P1036Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat GH receptor

Monoclonal Antibody for Rat GH receptor

Protein for Rat GH receptor

Cat.:

R1036h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Rat GH receptor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Regulation of rat growth hormone receptor gene expression."
Mathews L.S. , Enberg B. , Norstedt G.
J. Biol. Chem.264:9905-9910(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Liver.
2.

"The growth hormone-binding protein in rat serum is an alternatively spliced form of the rat growth hormone receptor."
Baumbach W.R. , Horner D.L. , Logan J.S.
Genes Dev.3:1199-1205(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ISOFORMS 1 AND 2)
3.

"Characterization of the short isoform of the growth hormone receptor synthesized by rat adipocytes."
Frick G.P. , Goodman H.M.
Endocrinology131:3083-3090(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Adipose tissue.
4.

"Structural comparison of a portion of the rat and mouse growth hormone receptor/binding protein genes."
Zhou Y. , He L. , Kopchick J.J.
Gene177:257-259(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 2)
5.

"Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase."
VanderKuur J.A. , Wang X. , Zhang L. , Campbell G.S. , Allevato G. , Billestrup N. , Norstedt G. , Carter-Su C.
J. Biol. Chem.269:21709-21717(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOMAIN JAK2 BINDING
6.

"Identification of phenylalanine 346 in the rat growth hormone receptor as being critical for ligand-mediated internalization and down-regulation."
Allevato G. , Billestrup N. , Goujon L. , Galsgaard E.D. , Norstedt G. , Postel-Vinay M.-C. , Kelly P.A. , Nielsen J.H.
J. Biol. Chem.270:17210-17214(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENDOCYTOSIS SIGNAL;MUTAGENESIS OF PHE-346
7.

"SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms."
Ram P.A. , Waxman D.J.
J. Biol. Chem.274:35553-35561(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SOCS FAMILY PROTEINS
8.

"Growth hormone-dependent phosphorylation of tyrosine 333 and/or 338 of the growth hormone receptor."
VanderKuur J.A. , Wang X. , Zhang L. , Allevato G. , Billestrup N. , Carter-Su C.
J. Biol. Chem.270:21738-21744(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION BY JAK2
9.

"Growth hormone-induced tyrosyl phosphorylation and deoxyribonucleic acid binding activity of Stat5A and Stat5B."
Smit L.S. , Vanderkuur J.A. , Stimage A. , Han Y. , Luo G. , Yu-Lee L.-Y. , Schwartz J. , Carter-Su C.
Endocrinology138:3426-3434(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;STAT5 ACTIVATION

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